The effects of external beam radiotherapy on endocrine function in patients with carcinoma of the prostate

P. W. Grigsby, C. A. Perez

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

Serum levels of testosterone, dihydrotestosterone, and follicle-stimulating and luteinizing hormones were determined prospectively in 59 patients with carcinoma of the prostate treated curatively with external beam radiotherapy. Hormone levels were determined before the initiation of therapy and up to 2 years following completion of therapy. Testosterone levels remained unchanged but dihydrotestosterone levels decreased slightly. Follicle-stimulating and luteinizing hormone levels increased significantly during therapy and remained elevated for up to 2 years after therapy. These findings are consistent with low dose irradiation of the testis.

Original languageEnglish
Pages (from-to)726-727
Number of pages2
JournalJournal of Urology
Volume135
Issue number4
DOIs
StatePublished - 1986

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