The effects of beryllium and other adjuvants on Ia expression by macrophages

K. Behbehani, D. I. Beller, E. R. Unanue

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

This study evaluated the effects of adjuvants on the expression of the Ia glycoproteins by macrophages. We reasoned that one way in which adjuvants might augment the immune response would be by increasing the representation of Ia-positive macrophages in tissues. The two major experimental approaches were to test in vivo whether the compounds affected the ration of Ia-positive:Ia-negative peritoneal macrophages, and to test in culture for their effects on the expression of macrophage membrane Ia.

Original languageEnglish
Pages (from-to)2047-2049
Number of pages3
JournalJournal of Immunology
Volume134
Issue number4
StatePublished - Dec 1 1985
Externally publishedYes

Fingerprint Dive into the research topics of 'The effects of beryllium and other adjuvants on Ia expression by macrophages'. Together they form a unique fingerprint.

  • Cite this