The effect of the background medium in microsphere-assisted microscopy

Arash Darafsheh, Jarod C. Finlay

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Scopus citations

Abstract

Microsphere-assisted microscopy can be incorporated onto conventional light microscopes allowing wide-field and flourescence imaging with enhanced resolution. The refractive index of the background medium in which the microsphere is placed plays an important role in imaging. In this work, we investigated the effect of the background medium containing the microsphere on imaging properties of the microspheres. We used finite-difference timedomain numerical simulation to investigate the photonic nanojet formation in a microlens. We showed that by fine tuning the refractive index of the background medium, the nanojet properties of a microlens can be optimized for applications where sharp focusing of light is needed. Our results provide a guideline for design optimization of novel microparticle-embedded optical devices.

Original languageEnglish
Title of host publicationNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIV
EditorsDan V. Nicolau, Dror Fixler, Alexander N. Cartwright
PublisherSPIE
ISBN (Electronic)9781510605954
DOIs
StatePublished - 2017
EventNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIV 2017 - San Francisco, United States
Duration: Jan 30 2017Feb 1 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10077
ISSN (Print)1605-7422

Conference

ConferenceNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIV 2017
Country/TerritoryUnited States
CitySan Francisco
Period01/30/1702/1/17

Keywords

  • FDTD
  • Microcylinder
  • Microscopy
  • Microsphere
  • Super-resolution

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