The effect of some contrast agents in the lung: An experimental study in the rat and dog

W. H. McAlister, F. B. Askin

Research output: Contribution to journalArticle

45 Scopus citations

Abstract

Radiographic and histologic studies were carried out in rats and dogs after the instillation of Barosperse, Hypaque-35%, metrizamide, MP10013 (a nonionic iodine-containing agent), and isotonic saline into the lungs of these animals. In addition, blood gases were examined using these agents in dogs. Given aspiration of larger quantities of the contrast agents, the nonionic iodine-containing agents (metrizamide and MP10013) were better tolerated and evoked less pulmonary response than either Hypaque-35% or Barosperse.

Original languageEnglish
Pages (from-to)245-251
Number of pages7
JournalAmerican Journal of Roentgenology
Volume140
Issue number2
DOIs
StatePublished - Jan 1 1983

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