TY - JOUR
T1 - The effect of hydrophobicity on the viscoelastic creep characteristics of poly(ethylene glycol)-acrylate hydrogels
AU - Ravi, N.
AU - Mitra, A.
AU - Zhang, L.
AU - Kannan, P.
AU - Szabó, B. A.
PY - 2002
Y1 - 2002
N2 - The creep behavior of hydrophobic poly(ethylene glycol)-acrylate hydrogels was well characterized by two Kelvin units in series, compared to the other various combinations of the linear viscoelastic elements investigated. The hydrogels were synthesized by reacting acrylate derivatives of poly(ethylene glycol) [PEG] with PEG-diacrylate as the crosslinking agent. By using different amounts of ophenoxy-PEG-acrylate in the monomer feed ratio, the hydrophobicity was varied. The extent of monomer conversion was greater than 95%, as determined by Raman spectroscopy. With increasing hydrophobicity, the elastic modulus of the hydrogels increased from 10.92 kPa to 35.10 kPa, and the density increased from 1.0004 g/cm3 to 1.0091 g/cm3, while the dimensional stability decreased from 1.55 to 1.48. Two Kelvin units in series well characterized the creep curve for various loads and time durations. The time constants were in the range of 1-2 s and approximately 300 s for the two Kelvin units. These hydrophobic hydrogels may be used as model tissues to determine the viscoelasticity of the human lens.
AB - The creep behavior of hydrophobic poly(ethylene glycol)-acrylate hydrogels was well characterized by two Kelvin units in series, compared to the other various combinations of the linear viscoelastic elements investigated. The hydrogels were synthesized by reacting acrylate derivatives of poly(ethylene glycol) [PEG] with PEG-diacrylate as the crosslinking agent. By using different amounts of ophenoxy-PEG-acrylate in the monomer feed ratio, the hydrophobicity was varied. The extent of monomer conversion was greater than 95%, as determined by Raman spectroscopy. With increasing hydrophobicity, the elastic modulus of the hydrogels increased from 10.92 kPa to 35.10 kPa, and the density increased from 1.0004 g/cm3 to 1.0091 g/cm3, while the dimensional stability decreased from 1.55 to 1.48. Two Kelvin units in series well characterized the creep curve for various loads and time durations. The time constants were in the range of 1-2 s and approximately 300 s for the two Kelvin units. These hydrophobic hydrogels may be used as model tissues to determine the viscoelasticity of the human lens.
UR - http://www.scopus.com/inward/record.url?scp=0040675753&partnerID=8YFLogxK
U2 - 10.1021/bk-2002-0833.ch016
DO - 10.1021/bk-2002-0833.ch016
M3 - Article
AN - SCOPUS:0040675753
SN - 0097-6156
VL - 833
SP - 233
EP - 247
JO - ACS Symposium Series
JF - ACS Symposium Series
ER -