TY - JOUR
T1 - The effect of head orientation on subarachnoid cerebrospinal fluid distribution and its implications for neurophysiological modulation and recording techniques
AU - Bijsterbosch, Janine D.
AU - Lee, Kwang Hyuk
AU - Hunter, Michael D.
AU - Wilkinson, Iain D.
AU - Farrow, Tom
AU - Barker, Anthony T.
AU - Woodruff, Peter W.R.
PY - 2013/3
Y1 - 2013/3
N2 - Gravitational forces may lead to local changes in subarachnoid cerebrospinal fluid (CSF) layer thickness, which has important implications for neurophysiological modulation and recording techniques. This study examines the effect of gravitational pull associated with different head positions on the distribution of subarachnoid CSF using structural magnetic resonance imaging. Images of seven subjects in three different positions (supine, left lateral and prone) were statistically compared. Results suggest that subarachnoid CSF volume decreases on the side of the head closest to the ground, due to downward brain movement with gravity. These findings warrant future research into currently unexplored gravitation-induced changes in regional subarachnoid CSF thickness.
AB - Gravitational forces may lead to local changes in subarachnoid cerebrospinal fluid (CSF) layer thickness, which has important implications for neurophysiological modulation and recording techniques. This study examines the effect of gravitational pull associated with different head positions on the distribution of subarachnoid CSF using structural magnetic resonance imaging. Images of seven subjects in three different positions (supine, left lateral and prone) were statistically compared. Results suggest that subarachnoid CSF volume decreases on the side of the head closest to the ground, due to downward brain movement with gravity. These findings warrant future research into currently unexplored gravitation-induced changes in regional subarachnoid CSF thickness.
KW - cerebrospinal fluid
KW - electroencephalography
KW - gravity
KW - head orientation
KW - transcranial magnetic stimulation
UR - http://www.scopus.com/inward/record.url?scp=84874470035&partnerID=8YFLogxK
U2 - 10.1088/0967-3334/34/3/N9
DO - 10.1088/0967-3334/34/3/N9
M3 - Article
C2 - 23400029
AN - SCOPUS:84874470035
SN - 0967-3334
VL - 34
SP - N9-N14
JO - Physiological Measurement
JF - Physiological Measurement
IS - 3
ER -