The effect of Dnaaf5 gene dosage on primary ciliary dyskinesia phenotypes

Keyphrases

• Gene Dosage 100%
• Primary Ciliary Dyskinesia 100%
• Cilia Function 100%
• Motor Assembly 100%
• Motile Cilia 66%
• Missense 66%
• Hydrocephalus 33%
• Gene Expression 33%
• Proteomic Analysis 33%
• Compound Heterozygous mutation 33%
• Frameshift 33%
• Embryonic Lethal 33%
• Homozygosity 33%
• Severe Disease 33%
• Mutant Cells 33%
• Regulatory Proteins 33%
• Mutant Mice 33%
• Structural Proteins 33%
• Improved Survival 33%
• Cilia 33%
• Missense mutation 33%
• Allele-specific 33%
• Disease Phenotype 33%
• Heterozygosity 33%
• Gene Coding 33%
• Transcriptional Analysis 33%
• Null Allele 33%
• Assembly Factor 33%
• Motile Ciliopathy 33%
• Dynein 33%
• Airway Cilia 33%
• Multiciliated 33%
• Variant Allele 33%
• Early Lethality 33%
• Clinical Trajectory 33%
• Heterogenic 33%
• Ultrastructure Analysis 33%
• CRISPR-Cas9 Genome Editing 33%
• Missense Variant 33%

Biochemistry, Genetics and Molecular Biology

• Gene Dosage 100%
• Cilium 100%
• Primary Ciliary Dyskinesia 100%
• Allele 66%
• Missense 50%
• Null Allele 33%
• CRISPR/Cas9 16%
• Homozygosity 16%
• Cell Mutant 16%
• Genome Editing 16%
• Structural Protein 16%
• Mouse Mutant 16%
• Missense Mutation 16%
• Dynein 16%
• Heterozygosity 16%
• Proteomics 16%