TY - JOUR
T1 - The effect of cerebrospinal fluid pressure on perilymphatic flow in the opened cochlea
AU - Salt, A. N.
AU - Stopp, P. E.
PY - 1979
Y1 - 1979
N2 - Scala tympani of guinea pigs was perfused with elevated potassium solutions whose concentrations were measured with ion-sensitive pipettes. It was noted that, upon spontaneous recovery, the concentration curve showed a 'break' approximately 3 min after perfusion ceased. When the CSF pressure was released by opening the cisterna magna, cochlear flow was markedly reduced, and the recovery curve became smoothly exponential, following a much slower return to control levels. This finding lends support to the idea proposed by Moscovitch, Gannon &Laszlo (1973) that longitudinal flow of CSF contributes to perilymph efflux in the patent cochlea.
AB - Scala tympani of guinea pigs was perfused with elevated potassium solutions whose concentrations were measured with ion-sensitive pipettes. It was noted that, upon spontaneous recovery, the concentration curve showed a 'break' approximately 3 min after perfusion ceased. When the CSF pressure was released by opening the cisterna magna, cochlear flow was markedly reduced, and the recovery curve became smoothly exponential, following a much slower return to control levels. This finding lends support to the idea proposed by Moscovitch, Gannon &Laszlo (1973) that longitudinal flow of CSF contributes to perilymph efflux in the patent cochlea.
UR - http://www.scopus.com/inward/record.url?scp=0018710996&partnerID=8YFLogxK
U2 - 10.3109/00016487909137160
DO - 10.3109/00016487909137160
M3 - Article
C2 - 495071
AN - SCOPUS:0018710996
SN - 0001-6489
VL - 88
SP - 198
EP - 202
JO - Acta Oto-Laryngologica
JF - Acta Oto-Laryngologica
IS - 1-6
ER -