The effect of carotid artery disease on the cerebrovascular response to physiologic stimulation

William J. Powers; Peter T. Fox; Marcus E. Raichle

doi:10.1212/wnl.38.9.1475

The effect of carotid artery disease on the cerebrovascular response to physiologic stimulation

William J. Powers, Peter T. Fox, Marcus E. Raichle

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Abstract

Eight of 16 patients with severe carotid artery disease, but no evidence of functional or structural brain damage, had abnormal regional cerebral blood flow (rCBF) responses to physiologic stimulation of sensorimotor cortex (unilateral reduction in six, abnormal diffuse increase in two). Thus, in patients with cerebrovascular disease the rCBF responses during physiologic tasks may not be reliable indicators of local neuronal activity.

Original language	English
Pages (from-to)	1475-1478
Number of pages	4
Journal	Neurology
Volume	38
Issue number	9
DOIs	https://doi.org/10.1212/wnl.38.9.1475
State	Published - Sep 1988

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title = "The effect of carotid artery disease on the cerebrovascular response to physiologic stimulation",

abstract = "Eight of 16 patients with severe carotid artery disease, but no evidence of functional or structural brain damage, had abnormal regional cerebral blood flow (rCBF) responses to physiologic stimulation of sensorimotor cortex (unilateral reduction in six, abnormal diffuse increase in two). Thus, in patients with cerebrovascular disease the rCBF responses during physiologic tasks may not be reliable indicators of local neuronal activity.",

author = "Powers, {William J.} and Fox, {Peter T.} and Raichle, {Marcus E.}",

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AU - Fox, Peter T.

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N2 - Eight of 16 patients with severe carotid artery disease, but no evidence of functional or structural brain damage, had abnormal regional cerebral blood flow (rCBF) responses to physiologic stimulation of sensorimotor cortex (unilateral reduction in six, abnormal diffuse increase in two). Thus, in patients with cerebrovascular disease the rCBF responses during physiologic tasks may not be reliable indicators of local neuronal activity.

AB - Eight of 16 patients with severe carotid artery disease, but no evidence of functional or structural brain damage, had abnormal regional cerebral blood flow (rCBF) responses to physiologic stimulation of sensorimotor cortex (unilateral reduction in six, abnormal diffuse increase in two). Thus, in patients with cerebrovascular disease the rCBF responses during physiologic tasks may not be reliable indicators of local neuronal activity.

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The effect of carotid artery disease on the cerebrovascular response to physiologic stimulation

Abstract

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