Natural killer (NK) cells play important roles in immunological processes, including early defense against viral infections. This review provides an overview of the dynamic in vivo life of NK cells from their development in the bone marrow to their mature peripheral responses and their ultimate demise, with particular emphasis on mouse NK cells and viral infections.

Original languageEnglish
Pages (from-to)405-429
Number of pages25
JournalAnnual Review of Immunology
StatePublished - Jun 7 2004


  • Development
  • Innate immunity
  • NK cells
  • Proliferation
  • Virus


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