The dynamic life of natural killer cells

Wayne M. Yokoyama; Sungjin Kim; Anthony R. French

doi:10.1146/annurev.immunol.22.012703.104711

The dynamic life of natural killer cells

Wayne M. Yokoyama, Sungjin Kim, Anthony R. French

Research output: Contribution to journal › Review article › peer-review

466 Scopus citations

Abstract

Natural killer (NK) cells play important roles in immunological processes, including early defense against viral infections. This review provides an overview of the dynamic in vivo life of NK cells from their development in the bone marrow to their mature peripheral responses and their ultimate demise, with particular emphasis on mouse NK cells and viral infections.

Original language	English
Pages (from-to)	405-429
Number of pages	25
Journal	Annual Review of Immunology
Volume	22
DOIs	https://doi.org/10.1146/annurev.immunol.22.012703.104711
State	Published - Jun 7 2004

Keywords

Development
Innate immunity
NK cells
Proliferation
Virus

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10.1146/annurev.immunol.22.012703.104711

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title = "The dynamic life of natural killer cells",

abstract = "Natural killer (NK) cells play important roles in immunological processes, including early defense against viral infections. This review provides an overview of the dynamic in vivo life of NK cells from their development in the bone marrow to their mature peripheral responses and their ultimate demise, with particular emphasis on mouse NK cells and viral infections.",

keywords = "Development, Innate immunity, NK cells, Proliferation, Virus",

author = "Yokoyama, {Wayne M.} and Sungjin Kim and French, {Anthony R.}",

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AU - Yokoyama, Wayne M.

AU - Kim, Sungjin

AU - French, Anthony R.

PY - 2004/6/7

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N2 - Natural killer (NK) cells play important roles in immunological processes, including early defense against viral infections. This review provides an overview of the dynamic in vivo life of NK cells from their development in the bone marrow to their mature peripheral responses and their ultimate demise, with particular emphasis on mouse NK cells and viral infections.

AB - Natural killer (NK) cells play important roles in immunological processes, including early defense against viral infections. This review provides an overview of the dynamic in vivo life of NK cells from their development in the bone marrow to their mature peripheral responses and their ultimate demise, with particular emphasis on mouse NK cells and viral infections.

KW - Development

KW - Innate immunity

KW - NK cells

KW - Proliferation

KW - Virus

UR - http://www.scopus.com/inward/record.url?scp=1842670944&partnerID=8YFLogxK

U2 - 10.1146/annurev.immunol.22.012703.104711

DO - 10.1146/annurev.immunol.22.012703.104711

M3 - Review article

C2 - 15032583

AN - SCOPUS:1842670944

SN - 0732-0582

VL - 22

SP - 405

EP - 429

JO - Annual Review of Immunology

JF - Annual Review of Immunology

ER -

The dynamic life of natural killer cells

Abstract

Keywords

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