The Depression Interview and Structured Hamilton (DISH): Rationale, development, characteristics, and clinical validity

Kenneth E. Freedland, Judith A. Skala, Robert M. Carney, James M. Raczynski, C. Barr Taylor, Carlos F. Mendes de Leon, Gail Ironson, James D. Hosking, Marston E. Youngblood, K. Ranga Rama Krishnan, Richard C. Veith

Research output: Contribution to journalArticlepeer-review

146 Scopus citations


Objective: The Depression Interview and Structured Hamilton (DISH) is a semistructured interview developed for the Enhancing Recovery in Coronary Heart Disease (ENRICHD) study, a multicenter clinical trial of treatment for depression and low perceived social support after acute myocardial infarction. The DISH is designed to diagnose depression in medically ill patients and to assess its severity on an embedded version of Williams' Structured Interview Guide for the Hamilton Depression scale (SIGH-D). This article describes the development and characteristics of the DISH and presents a validity study and data on its use in ENRICHD. Methods: In the validity study, the DISH and the Structured Clinical Interview for DSM-IV (SCID) were administered in randomized order to 57 patients. Trained interviewers administered the DISH, and clinicians administered the SCID. In ENRICHD, trained research nurses administered the DISH and recorded a diagnosis. Clinicians reviewed 42% of the interviews and recorded their own diagnosis. The Beck Depression Inventory (BDI) was administered in both studies. Results: In the validity study, the SCID diagnosis agreed with the DISH on 88% of the interviews (weighted κ = 0.86). In ENRICHD, the clinicians agreed with 93% of the research nurses' diagnoses. The BDI and the Hamilton depression scores derived from the DISH in the two studies correlated 0.76 (p < .0001) in the validity study and 0.64 (p < .0001) in ENRICHD. Conclusions: These findings support the validity of the DISH as a semistructured interview to assess depression in medically ill patients. The DISH is efficient in yielding both a DSM-IV depression diagnosis and a 17-item Hamilton depression score.

Original languageEnglish
Pages (from-to)897-905
Number of pages9
JournalPsychosomatic Medicine
Issue number6
StatePublished - Nov 2002


  • Coronary disease
  • Depressive disorder
  • Myocardial infarction
  • Psychiatric status rating scales
  • Psychological tests


Dive into the research topics of 'The Depression Interview and Structured Hamilton (DISH): Rationale, development, characteristics, and clinical validity'. Together they form a unique fingerprint.

Cite this