TY - JOUR
T1 - The changing prevalence of comorbidity across the age spectrum
AU - Piccirillo, Jay F.
AU - Vlahiotis, Anna
AU - Barrett, Laurel B.
AU - Flood, Kellie L.
AU - Spitznagel, Edward L.
AU - Steyerberg, Ewout W.
N1 - Funding Information:
None of the authors have any conflicts of interest. This research was supported by a grant from the National Cancer Institute (R01 CA10479-01). Study sponsors had no involvement in study design, in the collection, analysis and interpretation of data, in the writing of the manuscript, or in the decision to submit the manuscript for publication.
Funding Information:
Dr. Piccirillo is a professor of otolaryngology, medicine, and occupational therapy and Director of the Clinical Outcomes Research Office at the Washington University in St. Louis School of Medicine. He is a graduate of the University of Vermont College of Medicine and the Albany (New York) Medical Center Otolaryngology Residency Training program. After residency, he completed a Robert Wood Johnson Clinical Scholars Fellowship in Clinical Epidemiology and Health Services Research at Yale University.He is certified by the American Board of Otolaryngology-Head and Neck Surgery, a member of the Triological Society, American Academy of Otolaryngology-Head and Neck Surgery, a Fellow of the American College of Surgeons, and a member of the National Quality Forum, Quality of Cancer Care Measures Project.He is an associate editor of the Archives of Otolaryngology-Head and Neck Surgery and was a member of the Editorial Board of Otolaryngology-Head and Neck Surgery.He has received NCI and American Cancer Society funding to improve the classification of patients with cancer and the evaluation of treatment effectiveness through the inclusion of comorbidity. He is currently studying the physical, functional, and cognitive deficits associated with senior adult oncology patients.
PY - 2008/8
Y1 - 2008/8
N2 - The purpose of the research was to demonstrate that comorbid health conditions disproportionately affect elderly cancer patients. Descriptive analyses and stacked area charts were used to examine the prevalence and severity of comorbid ailments by age of 27,506 newly diagnosed patients treated at one of eight cancer centers between 1998 and 2003. Hypertension was the most common ailment in all patients, diabetes was the second most prevalent ailment in middle-aged patients, and previous solid tumor(s) were the second most prevalent ailment in patients aged 74 and older. Although the prevalence and severity of comorbid ailments including dementia and congestive heart failure increased with age, some comorbidities such as HIV/AIDS and obesity decreased. Advances in cancer interventions have increased survivorship, but the impact of the changing prevalence and severity of comorbidities at different ages has implications for targeted research into targeted clinical and psychosocial interventions.
AB - The purpose of the research was to demonstrate that comorbid health conditions disproportionately affect elderly cancer patients. Descriptive analyses and stacked area charts were used to examine the prevalence and severity of comorbid ailments by age of 27,506 newly diagnosed patients treated at one of eight cancer centers between 1998 and 2003. Hypertension was the most common ailment in all patients, diabetes was the second most prevalent ailment in middle-aged patients, and previous solid tumor(s) were the second most prevalent ailment in patients aged 74 and older. Although the prevalence and severity of comorbid ailments including dementia and congestive heart failure increased with age, some comorbidities such as HIV/AIDS and obesity decreased. Advances in cancer interventions have increased survivorship, but the impact of the changing prevalence and severity of comorbidities at different ages has implications for targeted research into targeted clinical and psychosocial interventions.
KW - Cancer
KW - Comorbidities
KW - Epidemiology
UR - http://www.scopus.com/inward/record.url?scp=45949108450&partnerID=8YFLogxK
U2 - 10.1016/j.critrevonc.2008.01.013
DO - 10.1016/j.critrevonc.2008.01.013
M3 - Review article
C2 - 18375141
AN - SCOPUS:45949108450
SN - 1040-8428
VL - 67
SP - 124
EP - 132
JO - Critical Reviews in Oncology/Hematology
JF - Critical Reviews in Oncology/Hematology
IS - 2
ER -