TY - JOUR
T1 - The C-terminal ester of membrane anchored peptide ion channels affects anion transport
AU - Djedovic, Natasha
AU - Ferdani, Riccardo
AU - Harder, Egan
AU - Pajewska, Jolanta
AU - Pajewski, Robert
AU - Schlesinger, Paul H.
AU - Gokel, George W.
PY - 2003
Y1 - 2003
N2 - Five heptapeptide derivatives, [CH3(CH2)17]2NCOCH2OCH2CO-Gly-Gly-Gly-Pro-Gly-Gly-Gly-OR, in which R = ethyl, 2-propyl, heptyl, benzyl, and cyclohexylmethyl, were found to transport chloride anion through a phospholipid bilayer to varying extents dependent on the identity of R. It was concluded that the R group is a membrane anchor for the synthetic chloride channels.
AB - Five heptapeptide derivatives, [CH3(CH2)17]2NCOCH2OCH2CO-Gly-Gly-Gly-Pro-Gly-Gly-Gly-OR, in which R = ethyl, 2-propyl, heptyl, benzyl, and cyclohexylmethyl, were found to transport chloride anion through a phospholipid bilayer to varying extents dependent on the identity of R. It was concluded that the R group is a membrane anchor for the synthetic chloride channels.
UR - http://www.scopus.com/inward/record.url?scp=0344442304&partnerID=8YFLogxK
U2 - 10.1039/b312209n
DO - 10.1039/b312209n
M3 - Article
C2 - 14680212
AN - SCOPUS:0344442304
SN - 1359-7345
VL - 3
SP - 2862
EP - 2863
JO - Chemical Communications
JF - Chemical Communications
IS - 23
ER -