TY - JOUR
T1 - The association of HLA-B7 and HLA-B12 antigens with cup/disk ratio, family history of glaucoma, and intraocular pressure
AU - Shin, Dong H.
AU - Kass, Michael A.
AU - Becker, Bernard
N1 - Funding Information:
From the Glaucoma Center, Department of Ophthalmology, Washington University School of Medicine, St. Louis, Missouri. This study was supported in part by grant EY00336 from the National Eye Institute, and by a fellowship from Fight For Sight, Inc., New York, New York (Dr. Shin). Reprint requests to Bernard Becker, M.D., Glaucoma Center, Department of Ophthalmology, Washington University School of Medicine, 660S.Euclid, St. Louis, MO 63110.
PY - 1977/3
Y1 - 1977/3
N2 - The presence of either HLA-B7 or HLA-B12 antigens was associated with a higher prevalence of cup/disk ratios > 0.3 in the GG responders (intraocular pressure > 31 mm Hg after six weeks of topical dexamethasone 0.1%, four times daily) and in the combined NN-NG (intraocular pressure ≤ 31 mm Hg) groups. The presence of either antigen was associated with a higher prevalence of a family history of glaucoma in the GG group. No association was noted between the antigens and age, sex, race, or mean intraocular pressure in either of the groups studied.
AB - The presence of either HLA-B7 or HLA-B12 antigens was associated with a higher prevalence of cup/disk ratios > 0.3 in the GG responders (intraocular pressure > 31 mm Hg after six weeks of topical dexamethasone 0.1%, four times daily) and in the combined NN-NG (intraocular pressure ≤ 31 mm Hg) groups. The presence of either antigen was associated with a higher prevalence of a family history of glaucoma in the GG group. No association was noted between the antigens and age, sex, race, or mean intraocular pressure in either of the groups studied.
UR - http://www.scopus.com/inward/record.url?scp=0017363408&partnerID=8YFLogxK
U2 - 10.1016/0002-9394(77)90731-0
DO - 10.1016/0002-9394(77)90731-0
M3 - Article
C2 - 848539
AN - SCOPUS:0017363408
SN - 0002-9394
VL - 83
SP - 347
EP - 349
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 3
ER -