TY - JOUR
T1 - The association between maternal cocaine use and placenta previa
AU - Macones, G. A.
AU - Sehdev, H. M.
AU - Parry, S.
AU - Morgan, M. A.
AU - Berlin, J. A.
PY - 1997
Y1 - 1997
N2 - OBJECTIVE: Our aim was to determine whether maternal cocaine exposure is a risk factor for placenta previa. STUDY DESIGN: In this case-control study, cases of placenta previa confirmed at delivery (ascertained by International Classification of Diseases, ninth revision. Clinical Modification, code- based search. N = 40) were compared with a random sample of patients without placenta previa (N = 80) in a ratio of two controls per case. Data on antecedent maternal cocaine use as well as other potential risk factors for placenta previa, were obtained from a review of the prenatal chart and the hospital record. Categorization of cocaine use was based on either patient self-report or urine toxicologic testing, or both. Multiple logistic regression was performed to assess me association between cocaine and placenta previa while we controlled for other variables. RESULTS: After the effects of other variables were adjusted for, maternal cocaine use was an independent risk factor for placenta previa (adjusted odds ratio = 4,39.95% confidence interval 1.17 to 16.4). Other significant risk factors included a history of cesarean section and prior elective abortion. CONCLUSION: These results suggest that cocaine use, as well as odor cesarean section, prior elective abortion, and parity, are associated with placenta previa.
AB - OBJECTIVE: Our aim was to determine whether maternal cocaine exposure is a risk factor for placenta previa. STUDY DESIGN: In this case-control study, cases of placenta previa confirmed at delivery (ascertained by International Classification of Diseases, ninth revision. Clinical Modification, code- based search. N = 40) were compared with a random sample of patients without placenta previa (N = 80) in a ratio of two controls per case. Data on antecedent maternal cocaine use as well as other potential risk factors for placenta previa, were obtained from a review of the prenatal chart and the hospital record. Categorization of cocaine use was based on either patient self-report or urine toxicologic testing, or both. Multiple logistic regression was performed to assess me association between cocaine and placenta previa while we controlled for other variables. RESULTS: After the effects of other variables were adjusted for, maternal cocaine use was an independent risk factor for placenta previa (adjusted odds ratio = 4,39.95% confidence interval 1.17 to 16.4). Other significant risk factors included a history of cesarean section and prior elective abortion. CONCLUSION: These results suggest that cocaine use, as well as odor cesarean section, prior elective abortion, and parity, are associated with placenta previa.
KW - Abortion
KW - Cesarean section
KW - Cocaine use
KW - Placenta previa
UR - http://www.scopus.com/inward/record.url?scp=0030734182&partnerID=8YFLogxK
U2 - 10.1016/S0002-9378(97)70022-X
DO - 10.1016/S0002-9378(97)70022-X
M3 - Article
C2 - 9396901
AN - SCOPUS:0030734182
SN - 0002-9378
VL - 177
SP - 1097
EP - 1100
JO - American journal of obstetrics and gynecology
JF - American journal of obstetrics and gynecology
IS - 5
ER -