TY - JOUR
T1 - The association between Chiari malformation Type I, spinal syrinx, and scoliosis
AU - Strahle, Jennifer
AU - Smith, Brandon W.
AU - Martinez, Melaine
AU - Bapuraj, J. Rajiv
AU - Muraszko, Karin M.
AU - Garton, Hugh J.L.
AU - Maher, Cormac O.
PY - 2015/6
Y1 - 2015/6
N2 - Object: Chiari malformation Type I (CM-I) is often found in patients with scoliosis. Most previous reports of CM-I and scoliosis have focused on patients with CM-I and a spinal syrinx. The relationship between CM-I and scoliosis in the absence of a syrinx has never been defined clearly. The authors sought to determine if there is an independent association between CM-I and scoliosis when controlling for syrinx status. Methods: The medical records of 14.118 Consecutive Patients Aged 18 Years Who Underwent Brain or Cervical Spine MRI at A Single Inst. in An 11-Yr. Span Were Reviewed to Identify Patients with CM-I, Scoliosis, And/or Syrinx. the Relationship between CM-I and Scoliosis Was Analyzed by Using Multivariate Regression Anal. and Controlling for Age, Sex, CM-I Status, and Syrinx Status. Results: in This Cohort, 509 Patients Had CM-I, 1740 Patients Had Scoliosis, and 243 Patients Had A Spin. Syrinx. the Presence of CM-I, the Presence of Syrinx, Older Age, and Female Sex Were Each Significantly Assoc. with Scoliosis in the Univariate Anal.. in the Multivariate Regression Anal., Older Age , Female Sex , and Syrinx Were Each Independently Assoc. with Scoliosis. CM-I Was Not Independently Assoc. with Scoliosis When Controlling for These Other Variables . Conclusions: A Syrinx Was Independently Assoc. with Scoliosis in A Large Pediat. Pop. Undergoing MRI. CM-I Was Not Independently Assoc. with Scoliosis When Controlling for Age, Sex, and Syrinx Status. because CM-I Is Not Independently Assoc. with Scoliosis, Scoliosis Should Not Necessarily Be Considered A Symptom of Low Cerebellar Tonsil Position in Patients Without A Syrinx. 2015 AANS.
AB - Object: Chiari malformation Type I (CM-I) is often found in patients with scoliosis. Most previous reports of CM-I and scoliosis have focused on patients with CM-I and a spinal syrinx. The relationship between CM-I and scoliosis in the absence of a syrinx has never been defined clearly. The authors sought to determine if there is an independent association between CM-I and scoliosis when controlling for syrinx status. Methods: The medical records of 14.118 Consecutive Patients Aged 18 Years Who Underwent Brain or Cervical Spine MRI at A Single Inst. in An 11-Yr. Span Were Reviewed to Identify Patients with CM-I, Scoliosis, And/or Syrinx. the Relationship between CM-I and Scoliosis Was Analyzed by Using Multivariate Regression Anal. and Controlling for Age, Sex, CM-I Status, and Syrinx Status. Results: in This Cohort, 509 Patients Had CM-I, 1740 Patients Had Scoliosis, and 243 Patients Had A Spin. Syrinx. the Presence of CM-I, the Presence of Syrinx, Older Age, and Female Sex Were Each Significantly Assoc. with Scoliosis in the Univariate Anal.. in the Multivariate Regression Anal., Older Age , Female Sex , and Syrinx Were Each Independently Assoc. with Scoliosis. CM-I Was Not Independently Assoc. with Scoliosis When Controlling for These Other Variables . Conclusions: A Syrinx Was Independently Assoc. with Scoliosis in A Large Pediat. Pop. Undergoing MRI. CM-I Was Not Independently Assoc. with Scoliosis When Controlling for Age, Sex, and Syrinx Status. because CM-I Is Not Independently Assoc. with Scoliosis, Scoliosis Should Not Necessarily Be Considered A Symptom of Low Cerebellar Tonsil Position in Patients Without A Syrinx. 2015 AANS.
KW - Chiari malformation Type I
KW - Scoliosis
KW - Spinal syrinx
UR - http://www.scopus.com/inward/record.url?scp=84938901163&partnerID=8YFLogxK
U2 - 10.3171/2014.11.PEDS14135
DO - 10.3171/2014.11.PEDS14135
M3 - Article
C2 - 26030330
AN - SCOPUS:84938901163
SN - 1933-0707
VL - 15
SP - 607
EP - 611
JO - Journal of Neurosurgery: Pediatrics
JF - Journal of Neurosurgery: Pediatrics
IS - 6
ER -