The association between Chiari malformation Type I, spinal syrinx, and scoliosis

Jennifer Strahle, Brandon W. Smith, Melaine Martinez, J. Rajiv Bapuraj, Karin M. Muraszko, Hugh J.L. Garton, Cormac O. Maher

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

Object: Chiari malformation Type I (CM-I) is often found in patients with scoliosis. Most previous reports of CM-I and scoliosis have focused on patients with CM-I and a spinal syrinx. The relationship between CM-I and scoliosis in the absence of a syrinx has never been defined clearly. The authors sought to determine if there is an independent association between CM-I and scoliosis when controlling for syrinx status. Methods: The medical records of 14.118 Consecutive Patients Aged 18 Years Who Underwent Brain or Cervical Spine MRI at A Single Inst. in An 11-Yr. Span Were Reviewed to Identify Patients with CM-I, Scoliosis, And/or Syrinx. the Relationship between CM-I and Scoliosis Was Analyzed by Using Multivariate Regression Anal. and Controlling for Age, Sex, CM-I Status, and Syrinx Status. Results: in This Cohort, 509 Patients Had CM-I, 1740 Patients Had Scoliosis, and 243 Patients Had A Spin. Syrinx. the Presence of CM-I, the Presence of Syrinx, Older Age, and Female Sex Were Each Significantly Assoc. with Scoliosis in the Univariate Anal.. in the Multivariate Regression Anal., Older Age , Female Sex , and Syrinx Were Each Independently Assoc. with Scoliosis. CM-I Was Not Independently Assoc. with Scoliosis When Controlling for These Other Variables . Conclusions: A Syrinx Was Independently Assoc. with Scoliosis in A Large Pediat. Pop. Undergoing MRI. CM-I Was Not Independently Assoc. with Scoliosis When Controlling for Age, Sex, and Syrinx Status. because CM-I Is Not Independently Assoc. with Scoliosis, Scoliosis Should Not Necessarily Be Considered A Symptom of Low Cerebellar Tonsil Position in Patients Without A Syrinx. 2015 AANS.

Original languageEnglish
Pages (from-to)607-611
Number of pages5
JournalJournal of Neurosurgery: Pediatrics
Volume15
Issue number6
DOIs
StatePublished - Jun 2015

Keywords

  • Chiari malformation Type I
  • Scoliosis
  • Spinal syrinx

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