The antithrombotic efficacy of AT-1459, a novel, direct thrombin inhibitor, in rat models of venous and arterial thrombosis

Keyphrases

• Rat Model 100%
• Venous Thrombosis 100%
• Arterial Thrombosis 100%
• Direct Thrombin Inhibitors 100%
• Argatroban 80%
• Dalteparin 80%
• Vessel Patency 60%
• Bleeding Time 40%
• Antithrombotic Effect 40%
• Vehicle Groups 40%
• ID50 40%
• Group Value 40%
• Rapid Onset 20%
• Oral Administration 20%
• Thrombus 20%
• Inhibition Rate 20%
• Transection 20%
• Consecutive Days 20%
• Warfarin 20%
• Continuous Infusion 20%
• Plasma Concentration 20%
• Antithrombotic Agents 20%
• Bolus Injection 20%
• Intravenous Administration 20%
• Time of Concentration 20%
• Thrombus Formation 20%
• Onset of Action 20%
• Thrombosis Model 20%
• Iron(III) Chloride 20%
• Rat Tail 20%
• Hemorrhagic Effect 20%
• Clotting Time 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Anticoagulant Agent 100%
• Rat Model 100%
• Thrombin Inhibitor 100%
• Artery Thrombosis 100%
• Vein Thrombosis 100%
• Dalteparin 80%
• Argatroban 80%
• Bleeding 40%
• Thrombus 40%
• Warfarin 20%
• Clotting Time 20%
• Oral Administration 20%