The activity and toxicity of low dose clofarabine against relapsed or refractory myeloma

Geoffrey L. Uy; Michael H. Tomasson; Alisa Ruddell; John F. DiPersio; Ravi Vij

The activity and toxicity of low dose clofarabine against relapsed or refractory myeloma

Geoffrey L. Uy, Michael H. Tomasson, Alisa Ruddell, John F. DiPersio, Ravi Vij

Research output: Contribution to journal › Article › peer-review

Abstract

Eight patients with refractory multiple myeloma were treated with clofarabine 4 mg/m²/day on days 1-5 of a 28 day cycle. No objective evidence of antimyeloma activity was observed (median time to progression of 52 days). All patients experienced grade 3-4 neutropenia and a greater than 50% decrease in platelet counts during treatment.

Original language	English
Pages (from-to)	1581-1582
Number of pages	2
Journal	Haematologica
Volume	91
Issue number	11
State	Published - Nov 1 2006

Keywords

Clinical trial
Clofarabine
Multiple myeloma

Cite this

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abstract = "Eight patients with refractory multiple myeloma were treated with clofarabine 4 mg/m2/day on days 1-5 of a 28 day cycle. No objective evidence of antimyeloma activity was observed (median time to progression of 52 days). All patients experienced grade 3-4 neutropenia and a greater than 50% decrease in platelet counts during treatment.",

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AU - Ruddell, Alisa

AU - DiPersio, John F.

AU - Vij, Ravi

PY - 2006/11/1

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AB - Eight patients with refractory multiple myeloma were treated with clofarabine 4 mg/m2/day on days 1-5 of a 28 day cycle. No objective evidence of antimyeloma activity was observed (median time to progression of 52 days). All patients experienced grade 3-4 neutropenia and a greater than 50% decrease in platelet counts during treatment.

KW - Clinical trial

KW - Clofarabine

KW - Multiple myeloma

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AN - SCOPUS:33750963443

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JO - Haematologica

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ER -

The activity and toxicity of low dose clofarabine against relapsed or refractory myeloma

Abstract

Keywords

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