The Absence of Tryptophan Hydroxylase Activity in Blood Platelets

Jeremiah J. Morrissey; Margaret N. Walker; Walter Lovenberg

doi:10.3181/00379727-154-39702

The Absence of Tryptophan Hydroxylase Activity in Blood Platelets

Jeremiah J. Morrissey
, Margaret N. Walker
, Walter Lovenberg

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Under conditions that support maximal tryptophan hydroxylating activity in extracts from pineal glands and brain no hydroxylase activity could be detected in platelets. Furthermore, with systems that are adequate to measure serotonin synthesis in cultured pineal glands or whole cells, no serotonin synthetic capacity could be detected in human or rat blood platelets.

Original language	English
Pages (from-to)	496-499
Number of pages	4
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	154
Issue number	4
DOIs	https://doi.org/10.3181/00379727-154-39702
State	Published - Apr 1977

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title = "The Absence of Tryptophan Hydroxylase Activity in Blood Platelets",

abstract = "Under conditions that support maximal tryptophan hydroxylating activity in extracts from pineal glands and brain no hydroxylase activity could be detected in platelets. Furthermore, with systems that are adequate to measure serotonin synthesis in cultured pineal glands or whole cells, no serotonin synthetic capacity could be detected in human or rat blood platelets.",

author = "Morrissey, \{Jeremiah J.\} and Walker, \{Margaret N.\} and Walter Lovenberg",

year = "1977",

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T1 - The Absence of Tryptophan Hydroxylase Activity in Blood Platelets

AU - Morrissey, Jeremiah J.

AU - Walker, Margaret N.

AU - Lovenberg, Walter

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Y1 - 1977/4

N2 - Under conditions that support maximal tryptophan hydroxylating activity in extracts from pineal glands and brain no hydroxylase activity could be detected in platelets. Furthermore, with systems that are adequate to measure serotonin synthesis in cultured pineal glands or whole cells, no serotonin synthetic capacity could be detected in human or rat blood platelets.

AB - Under conditions that support maximal tryptophan hydroxylating activity in extracts from pineal glands and brain no hydroxylase activity could be detected in platelets. Furthermore, with systems that are adequate to measure serotonin synthesis in cultured pineal glands or whole cells, no serotonin synthetic capacity could be detected in human or rat blood platelets.

UR - https://www.scopus.com/pages/publications/0017684911

U2 - 10.3181/00379727-154-39702

DO - 10.3181/00379727-154-39702

M3 - Article

C2 - 300878

AN - SCOPUS:0017684911

SN - 0037-9727

VL - 154

SP - 496

EP - 499

JO - Proceedings of the Society for Experimental Biology and Medicine

JF - Proceedings of the Society for Experimental Biology and Medicine

IS - 4

ER -

The Absence of Tryptophan Hydroxylase Activity in Blood Platelets

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