The Absence of Tryptophan Hydroxylase Activity in Blood Platelets

Jeremiah J. Morrissey, Margaret N. Walker, Walter Lovenberg

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Under conditions that support maximal tryptophan hydroxylating activity in extracts from pineal glands and brain no hydroxylase activity could be detected in platelets. Furthermore, with systems that are adequate to measure serotonin synthesis in cultured pineal glands or whole cells, no serotonin synthetic capacity could be detected in human or rat blood platelets.

Original languageEnglish
Pages (from-to)496-499
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Issue number4
StatePublished - Apr 1977


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