Th17 cytokines and vaccine-induced immunity

Yinyao Lin, Samantha R. Slight, Shabaana A. Khader

Research output: Contribution to journalReview articlepeer-review

88 Scopus citations

Abstract

T helper type 17 (Th17) cells are a distinct lineage of T cells that produce the effector molecules IL-17, IL-17F, IL-21, and IL-22. Although the role of Th17 cells in primary immune responses against infections is well documented, there is growing evidence that the Th17 lineage maybe critical for vaccine-induced memory immune responses against infectious diseases. Here, we summarize recent progress in our understanding of the role of IL-17 in vaccine-induced immunity.

Original languageEnglish
Pages (from-to)79-90
Number of pages12
JournalSeminars in Immunopathology
Volume32
Issue number1
DOIs
StatePublished - Mar 2010

Keywords

  • Infection
  • Th17
  • Vaccine-induced immunity

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