@article{0fd3997c003b41a9821ed7eff71d0b20,
title = "Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa",
abstract = "T helper type 17 (Th17) cells are a distinct lineage of T cells that produce the effector molecules IL-17, IL-17F, IL-21, and IL-22. Although the role of Th17 cells in autoimmunity is well documented, there is growing evidence that the Th17 lineage and other interleukin (IL)-17-producing cells are critical for host defense against bacterial, fungal, and viral infections at mucosal surfaces. Here we summarize recent progress in our understanding of the function of IL-17-producing cells as a bridge between innate and adaptive immunity against infectious diseases at the mucosa.",
author = "Khader, {S. A.} and Gaffen, {S. L.} and Kolls, {J. K.}",
note = "Funding Information: This study was supported, in part, by the Pennsylvania Department of Health, Tobacco Formula Funding, and R01HL079142 and P50HL084932 from the National Institutes of Health to J.K.K.; Pennsylvania Department of Health, Tobacco Formula Funding, R00AI075106 from the National Institute of Allergy and Infectious Diseases and Children {\textquoteright} s Hospital of Pittsburgh to S.A.K. S.L.G. was supported by AR054389 and DE018822 from the National Institutes of Health.",
year = "2009",
doi = "10.1038/mi.2009.100",
language = "English",
volume = "2",
pages = "403--411",
journal = "Mucosal Immunology",
issn = "1933-0219",
number = "5",
}