Tetralogy of Fallot: Anatomic variants and their impact on surgical management

Angela M. Sharkey, Anshuman Sharma

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


Tetralogy of Fallot is the most common form of cyanotic congenital heart disease. In this condition, episodic worsening of hypoxemia results from dynamic shifts in physiology, so-called "Tet spells." The relative frequency of this lesion and the risks of exacerbating "Tet spells" make anesthetic management of this patient population challenging. The conduct of palliative and reparative cardiac surgery is determined in large part by the anatomic variations within the spectrum of this disorder, most notably the severity of right ventricular outflow tract obstruction. This review will address the impact that the anatomic substrate has on the perioperative management of this interesting patient population.

Original languageEnglish
Pages (from-to)88-96
Number of pages9
JournalSeminars in Cardiothoracic and Vascular Anesthesia
Issue number2
StatePublished - Jun 1 2012


  • cardiac anesthesia
  • cardiac surgery
  • children
  • congenital heart disease
  • neonate


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