Templated assembly of organic-inorganic materials using the core shell structure of the P22 bacteriophage

Biomimetic chemistry offers new approaches to supramolecular materials synthesis and assembly. We have demonstrated that an assembled viral protein cage, comprising an organic core-shell structure, can be used as a template for the size constrained synthesis of Fe₂O₃. Particle nucleation is directed by the inner scaffold protein layer, while the size constraints are determined by the outer capsid layer.