Television watching and colorectal cancer survival in men

Yin Cao, Jeffrey A. Meyerhardt, Andrew T. Chan, Kana Wu, Charles S. Fuchs, Edward L. Giovannucci

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Purpose: To assess the association between pre- and postdiagnostic time spent sitting watching TV as well as other sedentary behaviors (other sitting at home and at work/driving) and mortality from colorectal cancer or other causes, and overall mortality. Methods: We followed stage I–III colorectal cancer patients from the Health Professionals Follow-up Study (1986–2010). Cox models were used to calculate hazard ratios (HRs) and 95 % confidence intervals (CIs). Results: A total of 926 and 714 patients were included in the analysis of pre- and postdiagnostic TV watching, respectively, and 471 and 325 died during follow-up. Prolonged prediagnostic TV viewing was associated with increased risk of colorectal cancer-specific mortality independent of leisure-time physical activity. The HRs (95 % CIs) for 0–6, 7–13, 14–20, and ≥21 h/week were 1.00 (referent), 0.84 (0.56–1.25), 1.15 (0.75–1.78), and 2.13 (1.31–3.45) (ptrend = 0.01). The association was observed primarily among overweight and obese individuals. Prediagnostic TV watching was also associated with overall mortality within 5 years of diagnosis, largely due to the association with colorectal cancer mortality. Other prediagnostic sitting at home or at work/driving was not associated with mortality. Postdiagnostic TV viewing was associated with a nonsignificantly increased risk of colorectal cancer-specific mortality (HR for ≥21 vs 0–6 h/week = 1.45; 95 % CI 0.73–2.87) adjusting for TV viewing before diagnosis. Conclusion: Prolonged prediagnostic TV watching is associated with higher colorectal cancer-specific mortality independent of leisure-time physical activity among colorectal cancer patients.

Original languageEnglish
Pages (from-to)1467-1476
Number of pages10
JournalCancer Causes and Control
Volume26
Issue number10
DOIs
StatePublished - Oct 14 2015

Keywords

  • Colorectal cancer
  • Sedentary behavior
  • Survival
  • Television watching

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