TAVI en IA pura de válvula nativa: cuando indicaciones fuera de guías cumplen los requerimientos del paciente

Translated title of the contribution: Transcatheter aortic valve replacement in pure native aortic regurgitation: when off-label indications match the patient’s requirements

Javier A. Madrazo-Shiordia, Eduardo Martínez-Vázquez, Alejandro Zajarías-Kurschansky, Alan Zajarías, Félix Damas De Los Santos

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Objective: In recent years, transcatheter aortic valve replace (TAVR) has revolutionized the interventional treatment of aortic stenosis, however, only scarce evidence considers it as treatment for Aortic Regurgitation (AR). At present, the treatment of Pure AR of Native Valve with TAVR does not fall within the recommendations of international guidelines, as it poses multiple challenges with immediate and long-term variable and unpredictable results. The objective of this paper is to present the case of a patient with prohibitive operative risk that benefited of TAVR treatment for AR. Materials and methods: We present the case of a 79-year-old male patient who has severe Pure Native Aortic Valve Regurgitation, considered inoperable. Based on the heart team’s decision, TAVR was planned with the use of an Edwards SAPIEN 3 valve. After TAVR, the patient developed complete heart block and a pacemaker was implanted. He improved to NYHA II functional class. At 15-month follow-up, he suffered intracranial hemorrhage and passed away. Results and Conclusions: Management of patients with severe symptomatic AR with high surgical risk continues to be a special challenge. They have high mortality if left untreated with valvular change, despite medical treatment. Even though it is strictly off-label, TAVR might be a reasonable solution for a select type of patients who are considered inoperable due to surgical high mortality risk.

Translated title of the contributionTranscatheter aortic valve replacement in pure native aortic regurgitation: when off-label indications match the patient’s requirements
Original languageSpanish
Pages (from-to)438-445
Number of pages8
JournalArchivos de Cardiologia de Mexico
Volume92
Issue number4
DOIs
StatePublished - 2022

Keywords

  • Aortic regurgitation
  • Aortic valve insufficiency
  • TAVR
  • Transcatheter aortic valve replacement

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