Targeting V(D)J Recombinase: Putting a PHD to Work

Eugene M. Oltz, Oleg Osipovich

Research output: Contribution to journalShort survey

5 Scopus citations

Abstract

In this issue of Immunity, Liu et al. (2007) show that V(D)J recombinase binds chromatin marked by H3K4 trimethylation. Because this mark associates with active promoters, the finding forges a new link between transcription, epigenetics, and recombinase targeting during lymphocyte development.

Original languageEnglish
Pages (from-to)539-541
Number of pages3
JournalImmunity
Volume27
Issue number4
DOIs
StatePublished - Oct 26 2007

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