Targeting V(D)J Recombinase: Putting a PHD to Work

Eugene M. Oltz; Oleg Osipovich

doi:10.1016/j.immuni.2007.10.001

Targeting V(D)J Recombinase: Putting a PHD to Work

Eugene M. Oltz, Oleg Osipovich

Division of Laboratory and Genomic Medicine

Research output: Contribution to journal › Short survey › peer-review

6 Scopus citations

Abstract

In this issue of Immunity, Liu et al. (2007) show that V(D)J recombinase binds chromatin marked by H3K4 trimethylation. Because this mark associates with active promoters, the finding forges a new link between transcription, epigenetics, and recombinase targeting during lymphocyte development.

Original language	English
Pages (from-to)	539-541
Number of pages	3
Journal	Immunity
Volume	27
Issue number	4
DOIs	https://doi.org/10.1016/j.immuni.2007.10.001
State	Published - Oct 26 2007

Access to Document

10.1016/j.immuni.2007.10.001

Cite this

@article{cf674661782d4369945a931e4b09268e,

title = "Targeting V(D)J Recombinase: Putting a PHD to Work",

abstract = "In this issue of Immunity, Liu et al. (2007) show that V(D)J recombinase binds chromatin marked by H3K4 trimethylation. Because this mark associates with active promoters, the finding forges a new link between transcription, epigenetics, and recombinase targeting during lymphocyte development.",

author = "Oltz, {Eugene M.} and Oleg Osipovich",

year = "2007",

month = oct,

day = "26",

doi = "10.1016/j.immuni.2007.10.001",

language = "English",

volume = "27",

pages = "539--541",

journal = "Immunity",

issn = "1074-7613",

number = "4",

}

TY - JOUR

T1 - Targeting V(D)J Recombinase

T2 - Putting a PHD to Work

AU - Oltz, Eugene M.

AU - Osipovich, Oleg

PY - 2007/10/26

Y1 - 2007/10/26

N2 - In this issue of Immunity, Liu et al. (2007) show that V(D)J recombinase binds chromatin marked by H3K4 trimethylation. Because this mark associates with active promoters, the finding forges a new link between transcription, epigenetics, and recombinase targeting during lymphocyte development.

AB - In this issue of Immunity, Liu et al. (2007) show that V(D)J recombinase binds chromatin marked by H3K4 trimethylation. Because this mark associates with active promoters, the finding forges a new link between transcription, epigenetics, and recombinase targeting during lymphocyte development.

UR - http://www.scopus.com/inward/record.url?scp=35348964047&partnerID=8YFLogxK

U2 - 10.1016/j.immuni.2007.10.001

DO - 10.1016/j.immuni.2007.10.001

M3 - Short survey

C2 - 17967406

AN - SCOPUS:35348964047

SN - 1074-7613

VL - 27

SP - 539

EP - 541

JO - Immunity

JF - Immunity

IS - 4

ER -

Targeting V(D)J Recombinase: Putting a PHD to Work

Abstract

Access to Document

Other files and links

Fingerprint

Cite this