Targeting pre-synaptic tau accumulation: a new strategy to counteract tau-mediated synaptic loss and memory deficits

Maud Gratuze, David M. Holtzman

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Synaptic tau accumulation is believed to promote synaptic loss, which contributes to cognitive deficits in Alzheimer's disease and tauopathies. In this issue of Neuron, Largo-Barrientos et al. report that synaptic loss can be mitigated by lowering Synaptogyrin-3, a known mediator of tau binding to synaptic vesicles.

Original languageEnglish
Pages (from-to)741-743
Number of pages3
JournalNeuron
Volume109
Issue number5
DOIs
StatePublished - Mar 3 2021

Fingerprint

Dive into the research topics of 'Targeting pre-synaptic tau accumulation: a new strategy to counteract tau-mediated synaptic loss and memory deficits'. Together they form a unique fingerprint.

Cite this