Targeting immune–fibroblast cell communication in heart failure

Keyphrases

• Cell-cell Communication 100%
• Heart Failure 100%
• Fibroblasts 100%
• Activator protein-1 (AP-1) 40%
• Periostin (POSTN) 40%
• CCR2 20%
• Interleukin-1 Signaling 20%
• Myofibroblast 20%
• Human Heart 20%
• Tissue Fibrosis 20%
• Interleukin-1β 10%
• Molecular Mechanism 10%
• Macrophages 10%
• Dermal Fibroblasts 10%
• Monoclonal Antibody 10%
• Human Disease 10%
• Cardiac Disease 10%
• Monocytes 10%
• Myocardial Fibrosis 10%
• Infarcted 10%
• Disease-associated 10%
• Therapeutic Potential 10%
• Cardiac Fibroblasts 10%
• Organ Function 10%
• Cardiac Function 10%
• Healthy Donors 10%
• Distinct Population Segment 10%
• Disease Phenotype 10%
• Epitope Mapping 10%
• Multi-omics 10%
• Genetic Lineage Tracing 10%
• Cardiac Injury 10%
• Inflammatory Fibrosis 10%
• Spatial Transcriptomics 10%
• Type 2 Macrophages 10%
• Interleukin-1 Receptor 10%
• Human Dermis 10%
• Single-cell Gene Expression 10%
• Chromatin Accessibility 10%
• In Vivo Mouse Model 10%
• Targeting Inflammation 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Congestive Heart Failure 100%
• Transcription Factor RUNX2 100%
• Interleukin 1 75%
• Inflammation 50%
• Fibrosis 50%
• Gamma Chemokine 50%
• Chemokine Receptor 50%
• Diseases 50%
• Mouse Model 25%
• Monoclonal Antibody 25%
• Heart Disease 25%
• Epitope 25%
• Heart Injury 25%
• Heart Muscle Fibrosis 25%
• Interleukin 1 Receptor 25%

Immunology and Microbiology

• Cell Communication 100%
• Fibroblast 100%
• Transcription Factor RUNX2 33%
• Interleukin 1 25%
• Lineages 25%
• Macrophage 16%
• Gamma Chemokine 16%
• Chemokine Receptor 16%
• Myofibroblast 16%
• Inflammation 16%
• Mouse Model 8%
• Gene Expression 8%
• Monocyte 8%
• Monoclonal Antibody 8%
• Heart Function 8%
• Interleukin-1 Receptor 8%
• Transcriptomics 8%
• Epitope Mapping 8%
• Chromatin 8%