Targeted sequencing and identification of genetic variants in sporadic inclusion body myositis

Keyphrases

• Genetic Variants 100%
• Targeted Sequencing 100%
• Target Identification 100%
• Sporadic Inclusion Body Myositis (sIBM) 100%
• Dementia 40%
• Paget's Disease of Bone 40%
• Missense mutation 40%
• Clinically Significant 20%
• Amyotrophic Lateral Sclerosis 20%
• Minor Allele Frequency 20%
• Pathogenic mutations 20%
• Pathologic 20%
• Frontotemporal Dementia 20%
• Coding Variants 20%
• Family History 20%
• In Vivo Analysis 20%
• Autophagy 20%
• C9orf72 Repeat Expansion 20%
• Repeated Measures Analysis 20%
• Pathomechanism 20%
• Muscle Disease 20%
• Inclusion Body Myopathy 20%
• IBMPFD 20%
• Genetic Etiology 20%
• Missense 20%
• Genetic Evaluation 20%
• Hereditary Myopathy 20%
• Emery-Dreifuss muscular Dystrophy 20%
• Distal Myopathy 20%
• Myofibrillar Myopathy 20%
• VCP mutation 20%
• Neurodegenerative Disorders 20%
• C9orf72 Hexanucleotide Repeat Expansion 20%

Biochemistry, Genetics and Molecular Biology

• Genetic Divergence 100%
• Missense Mutation 100%
• C9orf72 100%
• Genetics 50%
• Minor Allele Frequency 50%
• Autophagy 50%
• Missense 50%
• Genetic Evaluation 50%

Neuroscience

• Muscle Disorder 100%
• Myositis 100%
• Genetics 100%
• Missense Mutation 40%
• Amyotrophic Lateral Sclerosis 20%
• In Vitro 20%
• Neurodegenerative Disorder 20%
• Autophagy 20%
• Allele Frequency 20%
• Muscular Dystrophy 20%