Targeted Radiopharmaceuticals: Advances in Radiopharmacology and Radiopharmacy

Cathy S. Cutler, Sally W. Schwarz

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Nuclear imaging is noninvasive and therefore unique in its ability to evaluate biological pathways and function at the molecular level without perturbing the systems under investigation. Other techniques require invasive, destructive sampling of cells and tissues that yields a nonuniform, static snapshot at a single point in time. Molecular imaging is used to elucidate basic biology, diagnose and stage disease, and evaluate the in vitro properties of proposed drugs and aid in their translation from the bench to the clinic. is requires evaluating the drugs in appropriate animal models to determine distribution, concentration, and clearance in organs and tissues over time, and this can be done most eciently and eectively by imaging. e ultimate goal is to develop a data set that can accurately predict what drug dose can be administered safely and eectively to humans.

Original languageEnglish
Title of host publicationTargeted Molecular Imaging
PublisherCRC Press
Pages91-109
Number of pages19
ISBN (Electronic)9781439841969
ISBN (Print)9781439841952
DOIs
StatePublished - Jan 1 2012

Fingerprint

Dive into the research topics of 'Targeted Radiopharmaceuticals: Advances in Radiopharmacology and Radiopharmacy'. Together they form a unique fingerprint.

Cite this