Targeted cancer therapeutics: The heartbreak of success

Research output: Contribution to journalShort survey

31 Scopus citations

Abstract

Tyrosine kinase inhibitors, widely hailed for their success as treatments for cancer, are also plagued by the issue of cardiotoxic side effects. The mechanism behind the heart damage now comes to light for one such inhibitor, imatinib mesylate, also known as Gleevec (pages 908-916).

Original languageEnglish
Pages (from-to)881-882
Number of pages2
JournalNature medicine
Volume12
Issue number8
DOIs
StatePublished - Aug 1 2006
Externally publishedYes

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