Tackling Hypotheticals in Helminth Genomes

The International Molecular Helminthology Annotation Network (IMHAN); The IMHAN consortium authors include

doi:10.1016/j.pt.2017.11.007

Tackling Hypotheticals in Helminth Genomes

The International Molecular Helminthology Annotation Network (IMHAN)
, The IMHAN consortium authors include

Research output: Contribution to journal › Short survey › peer-review

30 Scopus citations

Abstract

Advancements in genome sequencing have led to the rapid accumulation of uncharacterized ‘hypothetical proteins’ in the public databases. Here we provide a community perspective and some best-practice approaches for the accurate functional annotation of uncharacterized genomic sequences.

Original language	English
Pages (from-to)	179-183
Number of pages	5
Journal	Trends in Parasitology
Volume	34
Issue number	3
DOIs	https://doi.org/10.1016/j.pt.2017.11.007
State	Published - Mar 2018

Keywords

CRISPR
RNAi
annotation
genomes
helminth
hypothetical genes

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10.1016/j.pt.2017.11.007

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@article{212a879b582e46e982af69757b5f6993,

title = "Tackling Hypotheticals in Helminth Genomes",

abstract = "Advancements in genome sequencing have led to the rapid accumulation of uncharacterized {\textquoteleft}hypothetical proteins{\textquoteright} in the public databases. Here we provide a community perspective and some best-practice approaches for the accurate functional annotation of uncharacterized genomic sequences.",

keywords = "CRISPR, RNAi, annotation, genomes, helminth, hypothetical genes",

author = "\{The International Molecular Helminthology Annotation Network (IMHAN)\} and \{The IMHAN consortium authors include\} and Nikola Palevich and Collette Britton and Laura Kamenetzky and Makedonka Mitreva and \{de Moraes Mour{\~a}o\}, Marina and Sasisekhar Bennuru and Thomas Quack and Scholte, \{Larissa Lopes Silva\} and Rahul Tyagi and Slatko, \{Barton E.\}",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Ltd",

year = "2018",

month = mar,

doi = "10.1016/j.pt.2017.11.007",

language = "English",

volume = "34",

pages = "179--183",

journal = "Trends in Parasitology",

issn = "1471-4922",

number = "3",

}

TY - JOUR

T1 - Tackling Hypotheticals in Helminth Genomes

AU - The International Molecular Helminthology Annotation Network (IMHAN)

AU - The IMHAN consortium authors include

AU - Palevich, Nikola

AU - Britton, Collette

AU - Kamenetzky, Laura

AU - Mitreva, Makedonka

AU - de Moraes Mourão, Marina

AU - Bennuru, Sasisekhar

AU - Quack, Thomas

AU - Scholte, Larissa Lopes Silva

AU - Tyagi, Rahul

AU - Slatko, Barton E.

PY - 2018/3

Y1 - 2018/3

N2 - Advancements in genome sequencing have led to the rapid accumulation of uncharacterized ‘hypothetical proteins’ in the public databases. Here we provide a community perspective and some best-practice approaches for the accurate functional annotation of uncharacterized genomic sequences.

AB - Advancements in genome sequencing have led to the rapid accumulation of uncharacterized ‘hypothetical proteins’ in the public databases. Here we provide a community perspective and some best-practice approaches for the accurate functional annotation of uncharacterized genomic sequences.

KW - CRISPR

KW - RNAi

KW - annotation

KW - genomes

KW - helminth

KW - hypothetical genes

UR - https://www.scopus.com/pages/publications/85039452705

U2 - 10.1016/j.pt.2017.11.007

DO - 10.1016/j.pt.2017.11.007

M3 - Short survey

C2 - 29249363

AN - SCOPUS:85039452705

SN - 1471-4922

VL - 34

SP - 179

EP - 183

JO - Trends in Parasitology

JF - Trends in Parasitology

IS - 3

ER -

Tackling Hypotheticals in Helminth Genomes

Abstract

Keywords

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