Systematic bias between blood pH instruments

J. H. Ladenson; C. H. Smith; D. N. Dietzler; J. E. Davis

doi:10.1093/clinchem/20.10.1341

Systematic bias between blood pH instruments

J. H. Ladenson
, C. H. Smith
, D. N. Dietzler
, J. E. Davis

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Measurement of tris (hydroxymethyl) aminomethane buffers and blood samples was used to compare the following commercial pH instruments: Corning Models 160 and 165, Instrumentation Laboratory, Inc. Model 313, and Radiometer Models E5021 and BMS 3MK2. These comparisons uncovered a systematic bias of 0.02 pH units in Instrumentation Laboratory, Inc. electrodes manufactured before April 1973. Other factors found to affect analytical results were the temperature of the saturated KCl salt bridge and reference electrode, the design of the temperature control system, and the buffer used to standardize the instruments.

Original language	English
Pages (from-to)	1341-1343
Number of pages	3
Journal	Clinical chemistry
Volume	20
Issue number	10
DOIs	https://doi.org/10.1093/clinchem/20.10.1341
State	Published - 1974

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10.1093/clinchem/20.10.1341

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abstract = "Measurement of tris (hydroxymethyl) aminomethane buffers and blood samples was used to compare the following commercial pH instruments: Corning Models 160 and 165, Instrumentation Laboratory, Inc. Model 313, and Radiometer Models E5021 and BMS 3MK2. These comparisons uncovered a systematic bias of 0.02 pH units in Instrumentation Laboratory, Inc. electrodes manufactured before April 1973. Other factors found to affect analytical results were the temperature of the saturated KCl salt bridge and reference electrode, the design of the temperature control system, and the buffer used to standardize the instruments.",

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T1 - Systematic bias between blood pH instruments

AU - Ladenson, J. H.

AU - Smith, C. H.

AU - Dietzler, D. N.

AU - Davis, J. E.

PY - 1974

Y1 - 1974

N2 - Measurement of tris (hydroxymethyl) aminomethane buffers and blood samples was used to compare the following commercial pH instruments: Corning Models 160 and 165, Instrumentation Laboratory, Inc. Model 313, and Radiometer Models E5021 and BMS 3MK2. These comparisons uncovered a systematic bias of 0.02 pH units in Instrumentation Laboratory, Inc. electrodes manufactured before April 1973. Other factors found to affect analytical results were the temperature of the saturated KCl salt bridge and reference electrode, the design of the temperature control system, and the buffer used to standardize the instruments.

AB - Measurement of tris (hydroxymethyl) aminomethane buffers and blood samples was used to compare the following commercial pH instruments: Corning Models 160 and 165, Instrumentation Laboratory, Inc. Model 313, and Radiometer Models E5021 and BMS 3MK2. These comparisons uncovered a systematic bias of 0.02 pH units in Instrumentation Laboratory, Inc. electrodes manufactured before April 1973. Other factors found to affect analytical results were the temperature of the saturated KCl salt bridge and reference electrode, the design of the temperature control system, and the buffer used to standardize the instruments.

UR - https://www.scopus.com/pages/publications/0016276218

U2 - 10.1093/clinchem/20.10.1341

DO - 10.1093/clinchem/20.10.1341

M3 - Article

C2 - 4416037

AN - SCOPUS:0016276218

SN - 0009-9147

VL - 20

SP - 1341

EP - 1343

JO - Clinical chemistry

JF - Clinical chemistry

IS - 10

ER -

Systematic bias between blood pH instruments

Abstract

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