System modeling of a DOI-capable half-ring PET insert device for breast cancer imaging

Daniel B. Keesing, Debashish Pal, Joseph A. O'Sullivan, Sergey Komarov, Heyu Wu, Yuan Chuan Tai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations

Abstract

We have developed a new type of PET insert system that, when integrated into a whole-body PET scanner, offers the possibility of imaging the breast and chest wall region with higher resolution and sensitivity than a whole-body PET scanner alone. The focus of this paper is to describe a system model that can be used within a fully 3D iterative reconstruction algorithm to accurately model the measured data. We have modeled the most important components of the system matrix, includingthe spatially-variant geometric factor, inter-crystal penetration, and body attenuation. Due to the irregular sampling of the insert system, we compute the system matrix using the native detector geometry. Based on subdividing each detector volume into subvolumes, we show that this approach can model DOl crystals and non-DOl crystals under a common framework. We present some of our first results using data acquired by the physical PET insert system. More detailed modeling or normalization strategies will need to be employed to obtain the most benefit from the reconstruction algorithm.

Original languageEnglish
Title of host publication2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
Pages4218-4222
Number of pages5
DOIs
StatePublished - Dec 1 2008
Event2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008 - Dresden, Germany
Duration: Oct 19 2008Oct 25 2008

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Conference

Conference2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
CountryGermany
CityDresden
Period10/19/0810/25/08

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    Keesing, D. B., Pal, D., O'Sullivan, J. A., Komarov, S., Wu, H., & Tai, Y. C. (2008). System modeling of a DOI-capable half-ring PET insert device for breast cancer imaging. In 2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008 (pp. 4218-4222). [4774213] (IEEE Nuclear Science Symposium Conference Record). https://doi.org/10.1109/NSSMIC.2008.4774213