Synthesis of 2H,2H-perfluoroalkyl and 2H-perfluoroalkenyl carboxylic acids and amides

Samuel Achilefu, Laurence Mansuy, Claude Selve, Sylvie Thiebaut

Research output: Contribution to journalArticle

54 Scopus citations

Abstract

An efficient and convenient procedure for the synthesis of 2-perfluoroalkyl ethanoic acids by direct oxidation of 2-perfluoroalkyl ethanols with Jones' reagent ( CrO3 H2SO4 is described. Treatment of the acids with aqueous sodium hydroxide gave 3-perfluoroalkyl, 3-fluoro-2,3-propenyl carboxylic acids which may be used for the preparation of the corresponding chlorides and amides.

Original languageEnglish
Pages (from-to)19-26
Number of pages8
JournalJournal of Fluorine Chemistry
Volume70
Issue number1
DOIs
StatePublished - Jan 1995
Externally publishedYes

Keywords

  • 2-Perfluoroalkyl ethanoic acids
  • IR spectroscopy
  • Jones' reagent
  • NMR spectroscopy
  • Synthesis

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