Synthesis of 2H,2H-perfluoroalkyl and 2H-perfluoroalkenyl carboxylic acids and amides

Samuel Achilefu; Laurence Mansuy; Claude Selve; Sylvie Thiebaut

doi:10.1016/0022-1139(94)03084-D

Synthesis of 2H,2H-perfluoroalkyl and 2H-perfluoroalkenyl carboxylic acids and amides

Samuel Achilefu, Laurence Mansuy, Claude Selve, Sylvie Thiebaut

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

An efficient and convenient procedure for the synthesis of 2-perfluoroalkyl ethanoic acids by direct oxidation of 2-perfluoroalkyl ethanols with Jones' reagent ( CrO₃ H₂SO₄ is described. Treatment of the acids with aqueous sodium hydroxide gave 3-perfluoroalkyl, 3-fluoro-2,3-propenyl carboxylic acids which may be used for the preparation of the corresponding chlorides and amides.

Original language	English
Pages (from-to)	19-26
Number of pages	8
Journal	Journal of Fluorine Chemistry
Volume	70
Issue number	1
DOIs	https://doi.org/10.1016/0022-1139(94)03084-D
State	Published - Jan 1995

Keywords

2-Perfluoroalkyl ethanoic acids
IR spectroscopy
Jones' reagent
NMR spectroscopy
Synthesis

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10.1016/0022-1139(94)03084-D

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title = "Synthesis of 2H,2H-perfluoroalkyl and 2H-perfluoroalkenyl carboxylic acids and amides",

abstract = "An efficient and convenient procedure for the synthesis of 2-perfluoroalkyl ethanoic acids by direct oxidation of 2-perfluoroalkyl ethanols with Jones' reagent ( CrO3 H2SO4 is described. Treatment of the acids with aqueous sodium hydroxide gave 3-perfluoroalkyl, 3-fluoro-2,3-propenyl carboxylic acids which may be used for the preparation of the corresponding chlorides and amides.",

keywords = "2-Perfluoroalkyl ethanoic acids, IR spectroscopy, Jones' reagent, NMR spectroscopy, Synthesis",

author = "Samuel Achilefu and Laurence Mansuy and Claude Selve and Sylvie Thiebaut",

year = "1995",

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doi = "10.1016/0022-1139(94)03084-D",

language = "English",

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T1 - Synthesis of 2H,2H-perfluoroalkyl and 2H-perfluoroalkenyl carboxylic acids and amides

AU - Achilefu, Samuel

AU - Mansuy, Laurence

AU - Selve, Claude

AU - Thiebaut, Sylvie

PY - 1995/1

Y1 - 1995/1

N2 - An efficient and convenient procedure for the synthesis of 2-perfluoroalkyl ethanoic acids by direct oxidation of 2-perfluoroalkyl ethanols with Jones' reagent ( CrO3 H2SO4 is described. Treatment of the acids with aqueous sodium hydroxide gave 3-perfluoroalkyl, 3-fluoro-2,3-propenyl carboxylic acids which may be used for the preparation of the corresponding chlorides and amides.

AB - An efficient and convenient procedure for the synthesis of 2-perfluoroalkyl ethanoic acids by direct oxidation of 2-perfluoroalkyl ethanols with Jones' reagent ( CrO3 H2SO4 is described. Treatment of the acids with aqueous sodium hydroxide gave 3-perfluoroalkyl, 3-fluoro-2,3-propenyl carboxylic acids which may be used for the preparation of the corresponding chlorides and amides.

KW - 2-Perfluoroalkyl ethanoic acids

KW - IR spectroscopy

KW - Jones' reagent

KW - NMR spectroscopy

KW - Synthesis

UR - http://www.scopus.com/inward/record.url?scp=0002750695&partnerID=8YFLogxK

U2 - 10.1016/0022-1139(94)03084-D

DO - 10.1016/0022-1139(94)03084-D

M3 - Article

AN - SCOPUS:0002750695

SN - 0022-1139

VL - 70

SP - 19

EP - 26

JO - Journal of Fluorine Chemistry

JF - Journal of Fluorine Chemistry

IS - 1

ER -

Synthesis of 2H,2H-perfluoroalkyl and 2H-perfluoroalkenyl carboxylic acids and amides

Abstract

Keywords

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