An efficient and convenient procedure for the synthesis of 2-perfluoroalkyl ethanoic acids by direct oxidation of 2-perfluoroalkyl ethanols with Jones' reagent ( CrO3 H2SO4 is described. Treatment of the acids with aqueous sodium hydroxide gave 3-perfluoroalkyl, 3-fluoro-2,3-propenyl carboxylic acids which may be used for the preparation of the corresponding chlorides and amides.
- 2-Perfluoroalkyl ethanoic acids
- IR spectroscopy
- Jones' reagent
- NMR spectroscopy