Abstract
The reaction of o‐phthaldehyde with potassium cyanide and methylamine hydrochloride afforded 1‐cyano‐2‐methylisoindole (1) in 92% yield. Possible mechanism and supporting nmr, ir, mass spectrum and single X‐ray structure analysis for 1 are discussed. The X‐ray study revealed that the true structure of 1 can best be represented as a resonance hybrid of the canonical forms a, b, c and d.
Original language | English |
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Pages (from-to) | 1283-1286 |
Number of pages | 4 |
Journal | Journal of Heterocyclic Chemistry |
Volume | 20 |
Issue number | 5 |
DOIs | |
State | Published - Jan 1 1983 |