Synthesis and spectroscopy of near infrared fluorescent dyes for investigating dichromic fluorescence

Mingfeng Bai, Samuel Achilefu

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

We developed a series of near infrared (NIR) cyanine dyes to study dichromic fluorescence phenomenon, which provides new protocols for in vivo optical imaging. Preliminary spectroscopic studies show that dichromic fluorescence correlates with structural symmetry. This feature suggests the potential use of dichromic fluorescent molecules to study biological processes that can alter the structural symmetry of the molecular probes.

Original languageEnglish
Pages (from-to)280-284
Number of pages5
JournalBioorganic and Medicinal Chemistry Letters
Volume21
Issue number1
DOIs
StatePublished - Jan 1 2011

Keywords

  • Contrast agent
  • Cyanine dye
  • Dual fluorescence
  • NIR
  • Optical imaging

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