Synthesis and spectroscopic evaluation of PbS quantum dots emitting at 1300 nm for optimized imaging in optical window II

Alexander P. Aydt, Shane Blair, Hairong Zhang, Boris D. Chernomordik, Matthew C. Beard, Mikhail Y. Berezin

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations

Abstract

Contrast agents for optical imaging have traditionally been designed for the near-infrared (NIR) spectral range (700-900 nm, Optical Window I) where absorption and scattering of tissue are relatively low. Recently, another window beyond 1000 nm has been discovered known as Optical Window II or the extended Near Infrared (exNIR) with improved transparency. In this work, we present a method to synthesize quantum dots emitting at 1300 nanometers, the optimal wavelength. The quantum dots were synthesized in organic solvents, and a method of transforming them into water is discussed. Optical characterizations including absolute quantum yield and the fluorescence lifetime are presented.

Original languageEnglish
Title of host publicationReporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications VIII
EditorsRamesh Raghavachari, Samuel Achilefu
PublisherSPIE
ISBN (Electronic)9781628419573
DOIs
StatePublished - Jan 1 2016
EventReporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications VIII - San Francisco, United States
Duration: Feb 15 2016Feb 16 2016

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9723
ISSN (Print)1605-7422

Conference

ConferenceReporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications VIII
Country/TerritoryUnited States
CitySan Francisco
Period02/15/1602/16/16

Keywords

  • Deep Tissue Imaging
  • Near-Infrared
  • Optical Window II
  • Quantum Dots
  • Water Soluble

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