Synthesis and in vivo evaluation of 2 high-affinity ⁷⁶Br-labeled σ₂-receptor ligands

Keyphrases

• High Affinity 100%
• Ligand-receptor Binding 100%
• 2 Receptor 100%
• 76Br 100%
• In Vivo Evaluation 100%
• Compound II 37%
• 18F-fluorothymidine 31%
• Tumor 12%
• High Selectivity 12%
• Bromo 12%
• Compound 3 12%
• EMT6 12%
• Radiolabeled Compounds 12%
• Tumor-to-normal Tissue Ratio 12%
• Liver 6%
• Tumor Cells 6%
• Kidney 6%
• Binding Ligand 6%
• Receptor Binding 6%
• Solid Tumors 6%
• Ethyl 6%
• Specific Activity 6%
• Breast Tumor 6%
• Non-specific Binding 6%
• High Specific Activity 6%
• Butyl 6%
• Benzamide 6%
• Biodistribution Studies 6%
• MicroPET Imaging 6%
• PET Radiotracers 6%
• Electrophilic 6%
• Mammary Adenocarcinoma 6%
• Allograft Tumors 6%

Neuroscience

• In Vivo 100%
• Fluorine-18 100%
• Receptor 100%
• Positron Emission Tomography 20%
• Cell Line 20%
• Receptor Binding 20%
• Benzamide 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Receptor 100%
• Bromine 76 100%
• Neoplasm 37%
• Fluorine 18 31%
• Solid Malignant Neoplasm 6%
• Biodistribution 6%
• Breast Tumor 6%
• Tracer 6%
• Benzamide 6%
• Breast Adenocarcinoma 6%
• Polyethylene Terephthalate 6%