Synthesis and evaluation of polyhydroxylated near-infrared carbocyanine molecular probes

Zongren Zhang, Samuel Achilefu

Research output: Contribution to journalArticlepeer-review

115 Scopus citations

Abstract

Equation presented. A new near-infrared (NIR) fluorescent molecular probe derived from indocarbocyanine dye and galactose was prepared, and the procedure was optimized. The presence of a nonionic polyhydroxyl moiety between hydrophobic groups enhances solubility and possibly minimizes aggregation in aqueous solutions. The structural framework of this molecule provides multivalent sites for labeling diverse molecules.

Original languageEnglish
Pages (from-to)2067-2070
Number of pages4
JournalOrganic Letters
Volume6
Issue number12
DOIs
StatePublished - Jun 10 2004

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