Swelling-induced residual stress and the mechanism of curling in articular cartilage in vitro

L. A. Setton, W. M. Lai, V. C. Mow

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

5 Scopus citations


The triphasic theory has been used to analyze the in vitro free-swelling behavior of two-dimensional strips of articular cartilage with an inhomogeneous distribution of negative fixed charge density. The results indicate that the model can predict the characteristic curling behavior of cartilage strips. The free swelling geometry demonstrated a dependence on aspect ratio of the strip length thickness, so that the curling or cartilage strips increased with decreasing cartilage thickness. It was concluded that a physiological variation in fixed charge density gives rise to a non-uniform distribution of residual stress and strain, and is thus responsible for the curling of excised samples in vitro. The mathematical solution presented in this study provides a means for calculating the residual strains, stresses and swelling pressures in the equilibrium free-swelling configuration and may prove useful in the development of an experimental protocol for measurement of the residual strains in vitro and in situ.

Original languageEnglish
Title of host publicationAdvances in Bioengineering
EditorsJohn M. Tarbell
PublisherPubl by ASME
Number of pages4
ISBN (Print)0791810313
StatePublished - 1993
EventProceedings of the 1993 ASME Winter Annual Meeting - New Orleans, LA, USA
Duration: Nov 28 1993Dec 3 1993

Publication series

NameAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED


ConferenceProceedings of the 1993 ASME Winter Annual Meeting
CityNew Orleans, LA, USA


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