TY - JOUR
T1 - Sweet sensation
T2 - Developing a single-cell fluorescent reporter of glycolytic heterogeneity
AU - Karloff, Diane B.
AU - Heemstra, Jennifer M.
N1 - Publisher Copyright:
© 2021 Elsevier Ltd
PY - 2021/11/18
Y1 - 2021/11/18
N2 - Conversion of in vitro selected aptamers into functional metabolic sensors is hampered by reduced in vivo aptamer binding and limited tunability of cellular metabolite levels. In this issue of Cell Chemical Biology, Ortega et al. (2021) construct RNA sensors of fructose-6-bisphosphate (FBP) that report on metabolite levels within single yeast cells.
AB - Conversion of in vitro selected aptamers into functional metabolic sensors is hampered by reduced in vivo aptamer binding and limited tunability of cellular metabolite levels. In this issue of Cell Chemical Biology, Ortega et al. (2021) construct RNA sensors of fructose-6-bisphosphate (FBP) that report on metabolite levels within single yeast cells.
UR - https://www.scopus.com/pages/publications/85118866568
U2 - 10.1016/j.chembiol.2021.10.013
DO - 10.1016/j.chembiol.2021.10.013
M3 - Article
C2 - 34798034
AN - SCOPUS:85118866568
SN - 2451-9456
VL - 28
SP - 1539
EP - 1541
JO - Cell Chemical Biology
JF - Cell Chemical Biology
IS - 11
ER -