Abstract
This study tested the hypothesis that the peripheral nerve in the presence of diabetes is more susceptible to chronic nerve compression than it is in the nondiabetic rat. A 1-cm length of sciatic nerve was subjected to chronic compression by banding with a Silastic tube in normal and in streptozotocin-induced diabetic rats. After six months of banding, both the amplitude and conduction velocity of the diabetic banded sciatic nerve were significantly reduced (P < 0.001) in comparison with the nondiabetic banded rats. These results suggest that in the presence of hyperglycemia, the peripheral nerve is more susceptible to chronic compression.
| Original language | English |
|---|---|
| Pages (from-to) | 117-119 |
| Number of pages | 3 |
| Journal | Annals of Plastic Surgery |
| Volume | 20 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1 1988 |