Survey of animal models in post-traumatic arthritis: Choosing the right model to answer the right question

Bridgette D. Furman; Kelly A. Kimmerling; Chia Lung Wu; Dianne Little; Farshid Guilak; Steven A. Olson

doi:10.1007/978-1-4899-7606-2_10

Survey of animal models in post-traumatic arthritis: Choosing the right model to answer the right question

Bridgette D. Furman, Kelly A. Kimmerling, Chia Lung Wu, Dianne Little, Farshid Guilak, Steven A. Olson

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

The selection of a model to study post-traumatic arthritis is a challenging and potentially confusing decision. This chapter was added specifically to address questions investigators may have when considering moving their work into an animal model. It is not possible to cover every possible species of animal that could be used. Therefore, this chapter provides a comprehensive review of the various aspects of arthritis after joint injury that can be studied in three commonly used species. This work provides an overview of what assays, information, and data can be available to the investigators. It is important that investigators are certain they will be able to collect data to address their research question before the investigation begins.

Original language	English
Title of host publication	Post-Traumatic Arthritis
Subtitle of host publication	Pathogenesis, Diagnosis and Management
Publisher	Springer US
Pages	113-118
Number of pages	6
ISBN (Electronic)	9781489976062
ISBN (Print)	9781489976055
DOIs	https://doi.org/10.1007/978-1-4899-7606-2_10
State	Published - Jan 1 2015

Keywords

Canine
Dog
Experimental model
Mice
Murine
Post-traumatic arthritis
Rabbit

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10.1007/978-1-4899-7606-2_10

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Survey of animal models in post-traumatic arthritis: Choosing the right model to answer the right question

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Keywords

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