TY - JOUR
T1 - Surgical, speech, and audiologic outcomes in patients with orofacial cleft and van der woude syndrome
AU - Kitchin, Spencer
AU - Grames, Lynn
AU - Naidoo, Sybill D.
AU - Skolnick, Gary
AU - Schoenborn, Alyssa
AU - Snyder-Warwick, Alison
AU - Patel, Kamlesh
N1 - Funding Information:
Research in this publication was supported by the National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health under Award Number K08NS096232 (AKSW). The authors report no conflicts of interest. Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s Web site (www.jcraniofa-cialsurgery.com). Copyright © 2019 by Mutaz B. Habal, MD ISSN: 1049-2275 DOI: 10.1097/SCS.0000000000005590
Publisher Copyright:
© 2019 by Mutaz B. Habal, MD.
PY - 2019
Y1 - 2019
N2 - Objective: The purpose of this study was to investigate the surgical, speech, and audiologic outcomes in patients with Van der Woude syndrome (VWS) and compare them to patients with nonsyndromic cleft palate with or without cleft lip (NS-CP±L) treated at the same institution. Design: Retrospective chart review. Setting: A single children's hospital at a major academic institution. Patients: The records of 18 patients with VWS who had been treated at a single institution from 1989 to 2017 have been retrospectively examined. Thirty-eight patients with NS-CP±L who were also treated at the same institution during that same time frame were selected to closely match sex and date of birth. Main Outcome Measures: Demographic, clinical, surgical, and speech pathology data were gathered from medical charts. Result: By age 4, 88% of subjects with VWS and 76% of subjects with NS-CP±L (P=0.732) had been, or were actively involved in, speech therapy. By age 10, 100% of remaining subjects with VWS and 58% of remaining subjects with NS-CP±L remained involved in speech therapy (P=0.027). About 33% of patients with VWS and 16% of patients with NSCP ±L had a secondary procedure for velopharyngeal dysfunction (VPD) (P=0.171). Conclusion: The VWS group had more than twice the rate of secondary procedures for VPD repair, and a higher rate of continuing involvement for speech therapy at age 10. No differences were found in the rate of participation in speech therapy at or by age 4.
AB - Objective: The purpose of this study was to investigate the surgical, speech, and audiologic outcomes in patients with Van der Woude syndrome (VWS) and compare them to patients with nonsyndromic cleft palate with or without cleft lip (NS-CP±L) treated at the same institution. Design: Retrospective chart review. Setting: A single children's hospital at a major academic institution. Patients: The records of 18 patients with VWS who had been treated at a single institution from 1989 to 2017 have been retrospectively examined. Thirty-eight patients with NS-CP±L who were also treated at the same institution during that same time frame were selected to closely match sex and date of birth. Main Outcome Measures: Demographic, clinical, surgical, and speech pathology data were gathered from medical charts. Result: By age 4, 88% of subjects with VWS and 76% of subjects with NS-CP±L (P=0.732) had been, or were actively involved in, speech therapy. By age 10, 100% of remaining subjects with VWS and 58% of remaining subjects with NS-CP±L remained involved in speech therapy (P=0.027). About 33% of patients with VWS and 16% of patients with NSCP ±L had a secondary procedure for velopharyngeal dysfunction (VPD) (P=0.171). Conclusion: The VWS group had more than twice the rate of secondary procedures for VPD repair, and a higher rate of continuing involvement for speech therapy at age 10. No differences were found in the rate of participation in speech therapy at or by age 4.
KW - Cleft lip
KW - Cleft palate
KW - Speech pathology
KW - Van der Woude
UR - http://www.scopus.com/inward/record.url?scp=85069882611&partnerID=8YFLogxK
U2 - 10.1097/SCS.0000000000005590
DO - 10.1097/SCS.0000000000005590
M3 - Article
C2 - 31299749
AN - SCOPUS:85069882611
SN - 1049-2275
VL - 30
SP - 1484
EP - 1487
JO - Journal of Craniofacial Surgery
JF - Journal of Craniofacial Surgery
IS - 5
ER -