TY - JOUR
T1 - Surgical considerations in infant lung transplantation
T2 - Challenges and opportunities
AU - Costello, John P.
AU - Carvajal, Horacio G.
AU - Abarbanell, Aaron M.
AU - Eghtesady, Pirooz
AU - Nath, Dilip S.
N1 - Publisher Copyright:
© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons
PY - 2021/1
Y1 - 2021/1
N2 - Lung transplantation is a crucial component in the treatment of end-stage lung disease in infants. Traditionally, most lung transplants have been performed in older children and adults, resulting in a scarcity of data for infant patients. To address the challenges unique to this age group, novel strategies to provide the best preoperative, intraoperative, and postoperative care for these youngest patients are paramount. We review recent advances in bridge-to-transplantation therapy, including the use of a paracorporeal lung assist device, and differences in surgical technique, including bronchial artery revascularization, for incorporation into the overarching treatment strategy for infants undergoing lung transplantation.
AB - Lung transplantation is a crucial component in the treatment of end-stage lung disease in infants. Traditionally, most lung transplants have been performed in older children and adults, resulting in a scarcity of data for infant patients. To address the challenges unique to this age group, novel strategies to provide the best preoperative, intraoperative, and postoperative care for these youngest patients are paramount. We review recent advances in bridge-to-transplantation therapy, including the use of a paracorporeal lung assist device, and differences in surgical technique, including bronchial artery revascularization, for incorporation into the overarching treatment strategy for infants undergoing lung transplantation.
KW - artificial organs/ support devices: lung
KW - clinical research/ practice
KW - lung disease: congenital
KW - lung transplantation/ pulmonology
KW - pediatrics
KW - surgical technique
UR - http://www.scopus.com/inward/record.url?scp=85091009554&partnerID=8YFLogxK
U2 - 10.1111/ajt.16282
DO - 10.1111/ajt.16282
M3 - Article
C2 - 32852866
AN - SCOPUS:85091009554
SN - 1600-6135
VL - 21
SP - 15
EP - 20
JO - American Journal of Transplantation
JF - American Journal of Transplantation
IS - 1
ER -