TY - JOUR
T1 - Surgery in the Older Patient with Breast Cancer
AU - Frebault, Julia
AU - Bergom, Carmen
AU - Kong, Amanda L.
N1 - Funding Information:
Funding Information This work was supported by the National Center for Research Resources, the National Center for Advancing Translational Sciences and the Office of the Director of the National Institutes of Health through Grant 8KL2TR000056 (CB).
Publisher Copyright:
© 2019, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2019/8/1
Y1 - 2019/8/1
N2 - Purpose of Review: Breast cancer incidence and mortality increase with age. Older patients (≥ 70) are often excluded from studies. Due to multiple factors, it is unclear whether this population is best-treated using standard guidelines. Here, we review surgical management in older women with breast cancer. Recent Findings: Geriatric assessments can guide treatment recommendations and aid in predicting survival and quality of life. Surgery remains a principal component of breast cancer treatment in older patients, though differences exist compared with younger women, including higher mastectomy rates and evidence-based support of omission of post-lumpectomy radiation or axillary dissection in subsets of patients. In those forgoing surgical management, there is increased use of endocrine therapy. Hospice is also a valuable element of end-of-life care. Summary: Physicians should utilize geriatric assessment to make treatment recommendations for older breast cancer patients, including omission of radiation therapy, alterations to standard surgeries, or enrollment in hospice care.
AB - Purpose of Review: Breast cancer incidence and mortality increase with age. Older patients (≥ 70) are often excluded from studies. Due to multiple factors, it is unclear whether this population is best-treated using standard guidelines. Here, we review surgical management in older women with breast cancer. Recent Findings: Geriatric assessments can guide treatment recommendations and aid in predicting survival and quality of life. Surgery remains a principal component of breast cancer treatment in older patients, though differences exist compared with younger women, including higher mastectomy rates and evidence-based support of omission of post-lumpectomy radiation or axillary dissection in subsets of patients. In those forgoing surgical management, there is increased use of endocrine therapy. Hospice is also a valuable element of end-of-life care. Summary: Physicians should utilize geriatric assessment to make treatment recommendations for older breast cancer patients, including omission of radiation therapy, alterations to standard surgeries, or enrollment in hospice care.
KW - Breast cancer
KW - Geriatric assessment
KW - Geriatric oncology
KW - Lumpectomy
KW - Older patients
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=85068001117&partnerID=8YFLogxK
U2 - 10.1007/s11912-019-0822-2
DO - 10.1007/s11912-019-0822-2
M3 - Review article
C2 - 31240413
AN - SCOPUS:85068001117
SN - 1523-3790
VL - 21
JO - Current oncology reports
JF - Current oncology reports
IS - 8
M1 - 69
ER -