Surgery for fulminant Clostridium difficile infection

Baddr Shakhsheer, John Alverdy

Research output: Contribution to journalArticlepeer-review


Fulminant Clostridium difficile infection is an important clinical entity for surgeons given the increasing incidence and severity of the disease worldwide. Indications for surgery have not been standardized, but a worsening clinical picture from serial examination, laboratory evaluation, or overall clinical status appears to warrant surgical intervention. Total abdominal colectomy with end ileostomy confers a modest survival advantage but historical mortality rates range from 35% to 80% in small series. Diverting loop ileostomy has recently emerged as a possible alternative with decreased mortality rates and the advantage of preserving the colon.

Original languageEnglish
Pages (from-to)150-152
Number of pages3
JournalSeminars in Colon and Rectal Surgery
Issue number3
StatePublished - Jan 1 2014


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