Surgery for benign insulinoma: An international review

Matthias Rothmund, Lucio Angelini, L. Michael Brunt, John R. Farndon, Glenn Geelhoed, Dimitrie Grama, Christian Herfarth, Edwin L. Kaplan, Felix Largiader, Francesco Morino, Hans Jürgen Peiper, Charles Proye, Hans Dietrich Röher, Klaus Rückert, Fritz Kümmerle, Norman W. Thompson, Jon A. van Heerden

Research output: Contribution to journalArticlepeer-review

152 Scopus citations


In a multiinstitutional review, data on 396 patients with benign solitary or multiple insulinomas operated on in 15 centers were collected. In these 396 patients, 419 laparotomies (375 primary procedures and 44 reoperations) were performed. The rate of unnecessary laparotomies was 1.7%. Complications occurred after 132 operations (31.5%), requiring 27 reinterventions (6.4%). Ten (2%) patients died within 30 days of surgery. The success rate of first procedures in the centers was 94.9%. After reoperation, all but 2 (99.5%) of these patients were cured. The overall cure rate including those patients who had their primary operations elsewhere was 97.5%.

Original languageEnglish
Pages (from-to)393-398
Number of pages6
JournalWorld journal of surgery
Issue number3
StatePublished - May 1990


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